I must be falling apart. Any ride over 100 miles my lower back is killing me. I thought this bike was supposed to be comfortable. I feel like 70 years old after a good ride. Won't even get into neck issues I get from this bike.....Don't get me wrong I love the zx14r, smile every ride.
My wrist start to bother me a little after about 30 minutes on the bike. Doesn't get any worse once the pain-tingles are there (up to 2 hour rides at this point). I think a lot of it depends on the size of the rider. I'm shorter, so I think more weight falls on my wrist (longer reach to the bars for me). I would suggest some core strengthening, particularly sit ups. I use my core to help alleviate some of the wrist pressure.